Hepatic STAT3 in brain-insulin action on hepatic glucose production

10/03/2006 23:06 Filed in: 2006
This paper published on "Cell Metabolism" titled " Role of hepatic STAT3 in brain-insulin action on hepatic glucose production" demonstrated a possible signaling target of insulin in brain which relays the suppression of gluconeogenesis onto liver. When STAT3 is knocked down in liver, the suppression of i.c.v. insulin on gluconeogenesis in liver is ameliorated. This suggests that the communication between brain and liver might target on STAT3 pathway.

Here is the link of the paper Cell Metabolism
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